Laboratory tests

Mitochondrial function testing

Look more closely at cellular energy metabolism. This assessment can combine a functional test of oxygen use in selected blood cells with additional markers of oxidative stress and nutrient status, depending on the agreed panel.

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Not currently listed at Miami. The team can tell you where it is available and what the alternatives are.

Mitochondrial function illustration

At a glance

What this involves at Miami

Not currently listed here

Scope and price are confirmed with the team before booking. Where a published price exists for your clinic, it is shown on the programme or clinic page.

A locally specified laboratory assessment of markers related to mitochondrial function.

The exact test or procedure, preparation, clinician and price are agreed for your location before booking.

In detail

Why this matters in HLC care

When energy and recovery are a concern, it helps to separate a measurement of cellular respiration from a symptom such as tiredness. In selected cases the assay adds a closer look at sampled blood cells, while the clinical assessment checks common and treatable causes of fatigue.

A broader report can also include separate antioxidant and oxidative-damage measurements, such as glutathione fractions and markers of lipid or DNA oxidation, alongside selected nutrients. These add context but do not show that one supplement or infusion is required. The ordered panel determines which of these measurements you receive.

What the functional test shows

Mitochondria help cells convert nutrients into usable energy. In the laboratory, selected blood cells are exposed to controlled changes in the respiratory pathway. The resulting oxygen-consumption curve shows how the sampled cells respond under those conditions.

The report may combine several respiratory parameters into an index. The individual parameters matter as well: an index is a summary of the assay, not a direct measurement of energy production in every muscle, organ or tissue.

How the result becomes useful

Persistent fatigue or poor recovery can have many causes. The physician relates this result to symptoms, medication, sleep, activity and standard investigations. It does not by itself diagnose a mitochondrial disease or establish the cause of unexplained symptoms.

If the result is used for follow-up, record the assay version and sampling conditions. Newer versions can change the index calculation, so a numerical difference between versions may not represent a biological change. Agree a meaningful follow-up question before repeating the test.

Illustrative example

Example functional profile

An illustrative example created to explain the report or care plan. Values and findings are fictional, are not personal results and are not treatment targets. Your report depends on the agreed service.

Illustrative example — fictional values, not a personal result, not a clinical target and not a normal range.

Schematic cell-respiration experiment

0501001234Experimental stageRelative oxygen use
Invented relative values illustrate successive laboratory conditions, not your metabolism over a day. Basal and maximum values are corrected for residual oxygen use when the assay defines those outputs.
Show the values behind this chart
Schematic cell-respiration experiment — values
Experimental stageRelative oxygen use
160
225
3100
410

Reading the experimental stages

Reading the experimental stages
StageConditionWhat it helps separate
1BaselineStarting cellular oxygen use
2ATP synthesis inhibitedATP-linked demand from remaining respiration
3Uncoupled maximumMaximum capacity under assay conditions
4Respiratory chain inhibitedResidual non-mitochondrial oxygen use

What the report describes

Illustrative report structure
MeasureIllustrative valueWhat it would indicate
Basal respirationIllustrative curveOxygen use by sampled cells under baseline conditions.
Spare capacityIllustrative rangeDifference between maximum and basal respiration.
Non-mitochondrial respirationIllustrative rangeResidual oxygen consumption after the respiratory chain is inhibited.

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